The potential for gene-editing to increase muscle growth in pigs: experiences with editing myostatin

Table 8 Muscle weights of myostatin heterozygous and wild type pigs

	MSTN^+/+1		MSTN^±1		SEM	P-value
	IGF2 G²	IGF2 A²	IGF2 G	IGF2 A		MSTN	IGF2	MSTN x IGF2
Longissimus dorsi, kg	2.95	3.35	3.72	3.92	0.115	< 0.01	< 0.01	0.36
% Chilled side wt	6.83	7.41	8.16	8.28	0.206	< 0.01	0.08	0.26
Psoas major, kg	0.40	0.45	0.47	0.51	0.023	< 0.01	0.03	0.75
% Chilled side wt	0.89	0.96	0.99	1.04	0.068	0.07	0.26	0.83
Semitendinosus, kg	0.55	0.58	0.57	0.64	0.028	0.07	0.02	0.24
% Chilled side wt	1.21	1.22	1.17	1.30	0.053	0.55	0.06	0.11
Triceps brachii, kg	1.43	1.44	1.48	1.52	0.108	0.37	0.81	0.72
% Chilled side wt	1.63	1.95	2.33	2.89	0.401	0.01	0.18	0.71

¹MSTN^+/+ = homozygous wild-type myostatin, MSTN^± = one edited myostatin allele
²IGF2 paternal G allele (IGF2 G) or paternal A allele (IGF2 A)

ISSN: 2662-4044